Laboratory for Synthetic Chemistry and Chemical Biology Limited (LSCCB) has developed a novel modular approach to access a wide range of potentially pharmaceutically active molecules containing trifluoromethyl-bearing five-membered ring structures via catalytic carbene insertion into C-H bond
Trifluoromethyl-bearing five-membered ring structures are widely present in newly designed drugs, but effective methods to access them remain scarce. We developed a new modular approach to obtain a wide range of trifluoromethyl-containing five-membered ring structures via catalytic carbene insertion into C-H bond
Laboratory for Synthetic Chemistry and Chemical Biology (LSCCB) is an R&D centre funded by Health@InnoHK progamme of Innovation and Technology Commission of HKSAR. Established in 2020, LSCCB is operated with tripartite joint collaboration of The University of Hong Kong, Imperial College London and Peking University. LSCCB aims at integrating chemical and biomedical sciences to develop new molecular medicines and diagnostic tools for the treatment and analysis of human diseases, in particular, cancer. LSCCB currently assembles more than 20 principal investigators for 4 major research programmes including (a) Synthetic Chemistry; (b) Chemical Biology of Natural Products and Chinese Medicine; (c) Metal Anticancer Medicine, Diagnostics and Theranostics; and (d) Multi-Omics and Innovative Analytical Technologies for InnoHealth.