Peptide/protein chemical synthesis and drug development

LSCCB
Overview

Pioneered the development of Ser/Thr ligation for protein chemical synthesis and peptide-drug late-state modification methods

  • Peptide/protein chemical synthesis and drug development 0
  • Peptide/protein chemical synthesis and drug development 1
  • Peptide/protein chemical synthesis and drug development 2
Problem addressed

Solve the bottleneck for protein chemical synthesis and expand synthetic proteins for therapeutic application

Innovation
  • Novel and effective peptide ligation method
Key impact
  • Expand the application of chemical synthesis for biomacromolecules
Award
  • Achievement Award of the Decade for Chinese Peptide Industry

Laboratory for Synthetic Chemistry and Chemical Biology (LSCCB) is an R&D centre funded by Health@InnoHK progamme of Innovation and Technology Commission of  HKSAR. Established in 2020, LSCCB is operated with tripartite joint collaboration of The University of Hong Kong, Imperial College London and Peking University. LSCCB aims at integrating chemical and biomedical sciences to develop new molecular medicines and diagnostic tools for the treatment and analysis of human diseases, in particular, cancer. LSCCB currently assembles more than 20 principal investigators for 4 major research programmes including (a) Synthetic Chemistry; (b) Chemical Biology of Natural Products and Chinese Medicine; (c) Metal Anticancer Medicine, Diagnostics and Theranostics; and (d) Multi-Omics and Innovative Analytical Technologies for InnoHealth.

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