Through research collaboration platform between The Hong Kong Polytechnic University and University of Waterloo, our research centre – Centre for Eye and Vision Research has established a machine learning system for predicting the physicochemical property of candidate small molecules for pharmaceuticals and drug evaluation.
To date, when predicting molecular properties, attention has focused on employing structural features owing to the perspective that structure affects functionality and because one can quickly generate a large number of molecular features from a simple SMILES string. This approach has limited accuracy because it fails to accurately account for how molecules interact with their environment.
The Centre for Eye and Vision Research (CEVR) is a research collaboration between The Hong Kong Polytechnic University and the University of Waterloo in Canada under the InnoHK initiative of the HKSAR Government. It is located at the Hong Kong Science Park, Shatin, Hong Kong. It is the first global hub performing ground-breaking research in five key areas Myopia and Eye Growth, Ocular Drug Discovery and Delivery, Vision Enhancement, Tear Film and Ocular Surface, and Advanced Optometric Technology. The mission of CEVR is to generate technologies to prevent vision loss in the aging population and preserve healthy vision.