Screening and analyzing method of p-phenylenediamine quinone substance and application thereof

This method addresses challenges such as the lack of commercial standards and the need for high specificity and reduced false positives.

• This method combines full scanning, full-ion fragmentation scanning (AIF), and neutral loss secondary mass spectrum scanning (NL dd-MS2) for comprehensive screening.
• Specific diagnostic ions and neutral loss fragments are used as markers to screen PPD-quinones, ensuring high specificity and reduced false positives.
• This approach includes steps like sample pre-treatment, HRMS analysis, and software-based data extraction and filtering.

• It provides a high efficiency, specificity, and applicability in identifying PPD-quinones in soil, air, and tire samples, providing critical insights into their environmental presence and potential health impacts.
• This approach is highly efficient, specific, and capable of reducing false positives, offering a significant advancement in the detection and characterization of emerging contaminants.

• The current invention can be developed to screen for both known and unknown compounds for environmental monitoring and identifying new contaminants.

• China Patent Publication No.: CN 118348132 A