Method and a System for Analyzing Neuropharmacology of a Drug
Overview
A drug screening system for analyzing neuropharmacology of a chemical without any prior knowledge by using whole brain activity mapping and machine learning based computational approaches.
Research completion
2018
Commercialisation opportunities
technology licensing agreement
Problem addressed
Drug screening is a method for identifying and verifying pharmaceutical effect of a chemical compound on living species. In general, it is necessary to perform multiple stages of the drug screen process from predicting the effect of an unknown drug to verifying the pharmacology of such drug before allowing the drug to be used as medication for human beings.
Innovation
- An automatic system of high throughput generating the brain activity maps in larval zebrafish representing changes of the brain activity under the influence of each of the plurality of known drugs and the chemical compound.
- The present invention relates to a method and a system for analyzing neuropharmacology of a drug, and particularly, although not exclusively, to a drug screening method that utilizes functional brain physiology phenotypes and computational bioinformatics analysis.
Key impact
- Discovery of new compounds for treating brain diseses
- Reposition of current drugs for treating brain diseases
- Phamacological analysis and prediction without prior chemical or molecular knowledge
Application
- Drug screening,reposition
- Pharmacology analysis and prediction
Patent
- US 2020/0077847 A1
City University of Hong Kong (CityU)
As one of the fastest growing universities in the world over the past decade, City University of Hong Kong (CityU) is recognised as a hub for innovation in research and professional education. CityU identifies solutions to critical global challenges by extending the frontiers of knowledge both within and beyond existing research paradigms.
The University’s highly qualified academics are drawn from all over the world, not only bringing a wealth of research and professional experience to the teaching programmes, but also contributing to the knowledge and technology advancement.
Enquiry
