The Institute for Tissue Engineering and Regenerative Medicine at The Chinese University of Hong Kong has developed a novel culture system comprising a combination of a mechanically robust hydrogel, tendon-specific culture media, and mechanical loading regimen for efficient differentiation of tenocytes from stem cells, that can be directly applied as a cell-based therapeutic to achieve robust, precise tendon healing.
Tissue-specific stem cell differentiation is a grand challenge in regenerative medicine. At present, it is highly challenging to produce tendon cells and maintain their phenotype over long-term. Our proprietary culture system can provide a 3D tendon biomimetic culture environment, complete with biological and biophysical cues for precise and efficient tendon differentiation.
Founded in 1963, The Chinese University of Hong Kong (CUHK) is a forward-looking comprehensive research university with a global vision and a mission to combine tradition with modernity, and to bring together China and the West. CUHK teachers and students hail from all around the world. Four Nobel laureates are associated with the university, and it is the only tertiary institution in Hong Kong with recipients of the Nobel Prize, Turing Award, Fields Medal and Veblen Prize sitting as faculty in residence. CUHK graduates are connected worldwide through an extensive alumni network. CUHK undertakes a wide range of research programmes in many subject areas, and strives to provide scope for all academic staff to undertake consultancy and collaborative projects with industry.