Phytonutrient-based Remedial Fluid for the Management of Hypertrophic and Keloid Scars

During wound repairing, the excessive extracellular matrix formation and deposition of scar tissues will result in raised scars such as hypertrophic scar and keloid scar. This will create aesthetic concern, restrict physical movement and may also lead to itching, tenderness, pain or even depression and anxiety. The present technology and its products could prevent the formation of raised scar.

• The phytonutrient-based remedial fluids consist of small-molecule flavanol glycosides extracted from ferns. The experiment results showed that it could significantly suppress the activation and proliferation of skin myofibroblasts in patients with hypertrophic scars or keloids.
• These small molecules could also largely reduce the deposition of extracellular matrix. As a result, the formation of raised scar can be prevented.

• The product developed from this technology is a safe, non-invasive and convenient approach to suppress hypertrophic and keloid scars.
• Since many scar treatment gel sheets or creams contain silicone, this natural, non-toxic product provides another option for the people who are allergic to silicone. The customer can be benefited from the herbal products with non-irritating, refreshing texture.

• Silver Medal at the International Exhibition of Inventions of Geneva 2022

• This phytonutrient-based formulation can be used in scar treatment in the form of skincare products such as a general topical agent or nano-mist.
• They could help shrink, soften and flatten the raised scars, especially for hypertrophic scars and keloids.

• US Patent No. US 9,260,466
• China Patent No. ZL 201410210304.0
• Hong Kong Patent No. HK1202058B