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Phytonutrient-based Remedial Fluid for the Management of Hypertrophic and Keloid Scars

Overview

The present technology is a series of phytonutrient-based remedial fluids, which can be used as a general topical agent or complemented with a nano sprayer, for the management of raised scars.

  • Phytonutrient-based Remedial Fluid for the Management of Hypertrophic and Keloid Scars 0
  • Phytonutrient-based Remedial Fluid for the Management of Hypertrophic and Keloid Scars 1
Commercialisation opportunities
Collaboration and partnership for clinical trials
Problem addressed

During wound repairing, the excessive extracellular matrix formation and deposition of scar tissues will result in raised scars such as hypertrophic scar and keloid scar. This will create aesthetic concern, restrict physical movement and may also lead to itching, tenderness, pain or even depression and anxiety. The present technology and its products could prevent the formation of raised scar.

Innovation
  • The phytonutrient-based remedial fluids consist of small-molecule flavanol glycosides extracted from ferns. The experiment results showed that it could significantly suppress the activation and proliferation of skin myofibroblasts in patients with hypertrophic scars or keloids.
  • These small molecules could also largely reduce the deposition of extracellular matrix. As a result, the formation of raised scar can be prevented.
Key impact
  • The product developed from this technology is a safe, non-invasive and convenient approach to suppress hypertrophic and keloid scars.
  • Since many scar treatment gel sheets or creams contain silicone, this natural, non-toxic product provides another option for the people who are allergic to silicone. The customer can be benefited from the herbal products with non-irritating, refreshing texture.
Award
  • Silver Medal at the International Exhibition of Inventions of Geneva 2022
Application
  • This phytonutrient-based formulation can be used in scar treatment in the form of skincare products such as a general topical agent or nano-mist.
  • They could help shrink, soften and flatten the raised scars, especially for hypertrophic scars and keloids.
Hong Kong Baptist University (HKBU)

Aspiring to be a leading, research-led, liberal arts University in Asia, Hong Kong Baptist University is committed to conducting world-leading investigations that extends the frontiers of knowledge, tackles global challenges and benefits the community at home and abroad. 

Pursuing research excellence is one of the priorities of the University’s Institutional Strategic Plan 2018-2028. The University keeps enhancing its capacity and strength to produce world-class research with an aim to bring significant impact to the society. 

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