A software for automated compressive vertebral fracture detection on elderly women’s lateral chest radiograph: Ofeye 1.0

Overview

Because OVF (osteoporotic vertebral fracture) in chest radiographs is commonly missed in reporting, we developed a software for automated detection of OVF on chest lateral chest radiograph. The software has a user-friendly interface and allows ‘batch processing’. Testing showed a false positive rate of 2.4% for all labelling, and a sensitivity of 93% counting cases with ≥moderate grades OVF.

Commercialisation opportunities

non-exclusive licensing

Problem addressed

Many guidelines suggest elderly women should have osteoporosis screening, which is not commonly taken by individuals. Chest radiographs are commonly taken for lung and heart diseases, while OVFs (osteoporotic vertebral fractures) are often unrecognized on chest radiographs especially when the radiographs were not ordered for skeletal conditions. We developed a software for automated detection of OVF on lateral chest radiograph.

Innovation

Automated detection of osteoporotic vertebral fracture on lateral chest radiograph

Key impact

low false positive rate
high sensitivity for moderate and severe grade osteoporotic vertebral fractures
batch processing function
fast computation speed

Application

Automated detection of compressive vertebral fracture on lateral chest radiograph
Automated detection of compressive vertebral fracture on spine bone densitometric images
Automated detection of traumatic vertebral fracture on spine radiograph.

Patent

China Patent: 202110883049.6

The Chinese University of Hong Kong (CUHK)

Founded in 1963, The Chinese University of Hong Kong (CUHK) is a forward-looking comprehensive research university with a global vision and a mission to combine tradition with modernity, and to bring together China and the West. CUHK teachers and students hail from all around the world. Four Nobel laureates are associated with the university, and it is the only tertiary institution in Hong Kong with recipients of the Nobel Prize, Turing Award, Fields Medal and Veblen Prize sitting as faculty in residence. CUHK graduates are connected worldwide through an extensive alumni network. CUHK undertakes a wide range of research programmes in many subject areas, and strives to provide scope for all academic staff to undertake consultancy and collaborative projects with industry.

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