Natural product, Dihydro-resveratrol for treating colorectal cancer and melanoma

The drug 5-Fluorouracil (5-FU) has been the first choice to treat colorectal cancer for years. In addition to the common side effects of chemotherapy, the usage of 5-FU may also lead to increased risk of infection and anaemia. In light of 5-FU's high cytotoxicity and low bioavailability, our technology may provide another option of anti-cancer drug with fewer side effects.

• In our experiments, it is demonstrated that D-res could provide a significant therapeutic effect on colorectal cancer without adverse effects through our observation. The therapeutic effect of this anti-cancer agent is comparable with that of 5-FU, but with much lower toxicity.
• Therefore, the D-res is an experimentally proven antitumor agent that can be prescribed safely to cancer patients even at much higher doses than 5-FU. In our toxicity study, the D-res shows no toxicity even at very high dose of 6000 mg/kg.

• Patients can benefit from a new and safe anti-cancer drug with lower toxicity than 5-FU. Undesirable side effects can be minimized too.
• D-res and its stilbenoid derivatives can be synthesized from Resveratrol, which is found naturally in many plants. They can also be developed as food dietary compounds for treating or preventing cancers.

• D-res or its stilbenoid derivatives can be used in treating several types of cancers including colorectal cancer and melanoma. It is safe to use even at a high dose.
• Besides, they can be developed as food dietary compounds for treating or preventing cancers.

• US Patent No. US 10,017,442