Antiviral Hydrophobic Surfaces via Laser-Structured Copper Nanoparticles

Overview

C2i and HKUST have developed an innovative strategy using laser-structured copper nanoparticles on hydrophobic surfaces to suppress virus transmission.

Commercialisation opportunities

technology licensing agreement

Problem addressed

1. High transmissibility of SARS-CoV-2
2. Over-reliance on active disinfection
3. Toxicity and environmental risks of copper nanoparticles (CuNPs)
4. Surface adhesion facilitating viral spread
5. Need for multifunctional surfaces
6. Scalability and practical application

Innovation

Combines copper nanoparticles (CuNPs) (antiviral/antibacterial) with laser-structured hydrophobic surfaces (self-cleaning) to repel and inactivate viruses.
Releases copper ions and generates reactive oxygen species (ROS) to degrade viral RNA, disrupt capsids, and inhibit replication. Provides broad-spectrum antimicrobial effects (viruses, bacteria, fungi).
Emphasizes precise control of CuNP dosage to balance efficacy with reduced environmental/human health risks (e.g., avoiding liver/kidney accumulation).

Key impact

Synergistic action of copper ions and ROS generation ensures broad-spectrum pathogen inactivation. Laser-structured surfaces modulate wettability to reduce viral adhesion physically.
Laser technology allows precise, customizable surface patterning on diverse materials (e.g., PE:Al composites).
Reduces SARS-CoV-2 transmission in frequently touched public areas (doorknobs, handrails, medical equipment). Lowers self-inoculation risks by minimizing viral persistence on surfaces.
Protects frontline workers (e.g., healthcare staff) through antiviral PPE and equipment. Promotes public confidence in shared spaces (offices, hospitals, transport systems).

Application

Coating masks, gloves, gowns, and surgical tools with CuNPs-hydrophobic surfaces to protect healthcare workers from viral exposure.
Applying the material on bed rails, IV poles, and diagnostic equipment to reduce SARS-CoV-2 persistence and cross-contamination in healthcare settings.
Applying on frequently touched surfaces in offices, schools, and transport hubs, e.g. doorknobs, handrails, elevator buttons, and touch screens.
PE:Al composites for manufacturing long-lasting, low-maintenance surfaces in factories and warehouses.

Centre for Immunology & Infection

Addressing Public Health Issues Posed by Emerging Infectious Diseases

The rise of infectious diseases poses a significant threat to human health and public health systems globally. With the objective of deepening the understanding of human response to viruses and diseases, the Centre for Immunology & Infection (C2i) will contribute to establishing Hong Kong as a global centre of excellence for precision medicine tailored to population strategies and formulate innovative solutions for public health challenges with special attention to emerging infectious diseases.

A major focus of C2i is to apply a new technology platform established by the Institut Pasteur to develop an Immune Report Card for individuals, which will help define the health of one’ s immune system — the first line defence mechanism against diseases. The work will take into consideration individual genetics, previous infection histories, resident microbiota, as well as personal lifestyle and environmental factors to come up with personalised patient management strategies and improve the effectiveness of future public health initiatives.

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