Biodegradable Magnesium-based Hybrid Implant

Overview

Redesign of conventional orthopaedic implants to incorporate magnesium-based components. This design keeps the mechanical stability of conventional implants while having the biological benefits of magnesium that would stimulate and facilitate bone healing and tissue regeneration.

  • Biodegradable Magnesium-based Hybrid Implant 0
  • Biodegradable Magnesium-based Hybrid Implant 1
  • Biodegradable Magnesium-based Hybrid Implant 2
Commercialisation opportunities
Open for licensing and collaboration
Problem addressed

Innovative Mg-based hybrid locking screw system with locking plate for fracture fixation. This system can enhance the healing of fracture with the biodegradable Mg-based hybrid locking screw while minimizes the chance of bone refracturing during implant removal.

Innovation
  • A novel approach to apply the biological effect of magnesium implantation on accelerate healing in weight-bearing bones
  • Degradation of Mg Inhibits Bacteria Proliferation
Key impact
  • Magnesium is biodegradable and would release different products during it degradation.
  • Implantation of magnesium implants at the fracture increases bone formation.
  • Our team developed magnesium-based hybrid locking plate system which are based on those implants that are available clinically.
  • Our system uses a Titanium locking plates and titanium screws. For one of the screws that are closest to the fracture, we have changed it to a screw which the head is made of Titanium while the screw body is made of magnesium.
Award
  • Gold Award, 2022 Special Edition of the Geneva International Exhibition of Inventions
  • Gold Award with the Congratulations of the Jury, 46th International Exhibition of Inventions of Geneva 2018
  • Gold Award with the Congratulations of the Jury, 44th International Exhibition of Inventions of Geneva 2016
  • Silver Award, 43th International Exhibition of Inventions of Geneva 2015
Application
  • Accelerate fracture healing in weight-bearing bones
  • High purity magnesium screw for fixation of bone flap in patients with osteonecrosis of the femoral head

Patent

  • Hybrid implant system and manufacturing method therefor (US10525173B2)
  • ZL201320005009.2
  • ZL201410090327.2
  • ZL202020284177X
The Chinese University of Hong Kong (CUHK)

Founded in 1963, The Chinese University of Hong Kong (CUHK) is a forward-looking comprehensive research university with a global vision and a mission to combine tradition with modernity, and to bring together China and the West. CUHK teachers and students hail from all around the world. Four Nobel laureates are associated with the university, and it is the only tertiary institution in Hong Kong with recipients of the Nobel Prize, Turing Award, Fields Medal and Veblen Prize sitting as faculty in residence. CUHK graduates are connected worldwide through an extensive alumni network. CUHK undertakes a wide range of research programmes in many subject areas, and strives to provide scope for all academic staff to undertake consultancy and collaborative projects with industry. 

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