A modified Chinese Medicine formulation for treating Alzheimer's disease


This invention is a patented formulation by modifying the Traditional Chinese Medicine (TCM) formulation, Huang-Lian-Jie-Du-Tang (HLJDT). It provides an effective, safe, and low-cost option for Alzheimer's disease (AD) treatment and improvement of memory disorders in AD patients.

  • A modified Chinese Medicine formulation for treating Alzheimer's disease
Commercialisation opportunities
technology licensing agreement
Problem addressed

Currently, there is no cure for Alzheimer's disease (AD) and none of the medications have been shown to be more effective than the others. We suggested a pharmacological treatment that addresses the key causer (i.e. Amyloid β-peptide in the brain) in the pathogenesis of AD.

  • The accumulation of protein plaques and fibrous nodules (i.e. amyloid β-peptide and tau aggregates) in the brain will lead to rapid death of neurons and deterioration of brain function. The modified HLJDT can reduce the accumulation of these matters, making it a potential treatment for neurodegenerative diseases like AD.
Key impact
  • HLJDT-M has a significant therapeutic and pharmacological effects in treating AD.
  • HLJDT-M is an effective, safe, and low-cost option that could give hope to patients with AD. It also helps prevent and delay the onset of AD.
  • HLJDT-M is a TCM recipe that could be a dietary therapy for Alzheimer's disease
  • HLJDT-M can be taken as a health supplement or a non-prescription medicine for the prevention of neurodegenerative diseases like AD.


  • US Patent No. 9,375,457
  • China Patent No. ZL 201410265207.1
  • Hong Kong Patent No. HK 1200119
  • Macao Patent No. J/002740
Hong Kong Baptist University (HKBU)

Aspiring to be a leading, research-led, liberal arts University in Asia, Hong Kong Baptist University is committed to conducting world-leading investigations that extends the frontiers of knowledge, tackles global challenges and benefits the community at home and abroad. 

Pursuing research excellence is one of the priorities of the University’s Institutional Strategic Plan 2018-2028. The University keeps enhancing its capacity and strength to produce world-class research with an aim to bring significant impact to the society.