Taxamairin Analogs And Methods Of Preparation And Use Thereof
Taxamairin Analogs And Methods Of Preparation And Use Thereof
Overview
HKBU has developed a technology on development, synthesis, and applications of Taxamairin compounds and their analogs as anti-cancer drugs.
Commercialisation opportunities
Non-exclusive licensing
Problem addressed
This method improves simplifies the process, reduces costs, and provides a reliable supply for research.
Innovation
A semi-synthetic strategy using carnosic acid is proposed as a scalable and practical approach for producing Taxamairin A, B, and their derivatives.
Taxamairin compounds are derived from natural sources and exhibit various biological activities, including anti-cancer properties.
Key impact
This method enables gram-scale production within a week, simplifies the process, and provides a reliable supply for further biological and pharmaceutical research.
Application
Taxamairin analogs have shown potential in treating cancers such as colon, pancreatic, lung, gastric and liver cancers.